Citalopram EP Impurity A CAS 64372-56-1
| CAS No. | 64372-56-1 |
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Citalopram EP Impurity A.
CATO supplies Citalopram EP Impurity A (CAS 64372-56-1), a pharmacopoeial impurity reference standard (molecular formula C20H23FN2O2, MW 342.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Citalopram EP Impurity A (C20H23FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Citalopram EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23FN2O2 |
| Molecular Weight | 342.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Citalopram Standards
- Citalopram Impurity 11 (CAS CATO-C4X-110911)
- Citalopram Impurity 14 (CAS CATO-C4X-110914)
- Citalopram Impurity 15 (CAS 488787-59-3)
- Citalopram Impurity 68 (CAS 481047-48-7)
- Citalopram Impurity 84 (CAS CATO-C4X-110984)
- Citalopram EP Impurity M (CAS 440121-09-5)
- Citalopram Nitrile Oxide (CAS 1346601-93-1)
- Citalopram EP Impurity B (Escitalopram EP Impurity B ) (CAS 411221-53-9)
Recommended Standards
- Alogliptin Impurity 51 (CAS 1133421-35-8)
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- TAME (CAS 901-47-3)
- Epalrestat Impurity 1 (CAS 130786-32-2)
- Cetirizine EP Impurity D DiHCl (CAS 856841-95-7)
- Emedastine lmpurity 26 (CAS CATO-C4X-226726)
- 1-(3,5-Dichloropyridin-2-yl)-1h-pyrazol-4-amine (CAS 1247532-79-1)
- Methyl 6-chloro-5-(difluoromethyl)nicotinate (CAS 1805304-08-8)
- Pixantrone (CAS 144510-96-3)
- 5-Chloropyrido[3,4-d]pyridazin-4(3H)-one (CAS 1824466-35-4)
- 2-Chloro-5-fluoro-4-(methylthio)-pyridine (CAS 1820741-49-8)
- 4-(2,4-Dichlorobenzoyl)-N',N'-dimethyl-1H-pyrrole-2-carbohydrazide (CAS 338977-16-5)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com