Vortioxetine Impurity 3 CAS 960203-41-2

Description

Compared with other compounds in its class, the molecular weight of 293.22 g/mol gives Vortioxetine Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Vortioxetine Impurity 3 (CAS 960203-41-2) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13BrS and a molecular weight of 293.22 g/mol.

The molecular framework of Vortioxetine Impurity 3 (C14H13BrS) is characterized by sulfur-containing functionality, bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Vortioxetine Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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