Rocuronium Impurity 17 CAS 963-75-7
| CAS No. | 963-75-7 |
| Molecular Formula | C19H28O |
| Molecular Weight | 272.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Rocuronium Impurity 17 (CAS 963-75-7, C19H28O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Rocuronium Impurity 17 (C19H28O) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H28O |
| Molecular Weight | 272.43 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Rocuronium Standards
- Rocuronium Impurity 16 (CAS 14935-81-0)
- Rocuronium Impurity 52 (CAS 82467-84-3)
- Rocuronium Impurity 48 (CAS 2562348-54-1)
- Rocuronium Impurity 34 (CAS CATO-C4X-124234)
- Rocuronium Impurity 46 (CAS CATO-C4X-124246)
- Rocuronium Impurity 48 (CAS CATO-C4X-124248)
- Rocuronium Impurity 26 (CAS CATO-C4X-124226)
- Rocuronium impurity 65 (CAS CATO-C4X-124265)
Recommended Standards
- 10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one 25824-80-0 A818041 (CAS 25824-80-0)
- Testosterone Impurity 23 (CAS CATO-C4X-243223)
- tert-Butyl (10-aminodecyl)carbamate (CAS 216961-61-4)
- Testosterone Impurity 48 (CAS 2602-86-0)
- Lumateperone impurity 58 (CAS CATO-C4X-220158)
- Labetalol Impurity 46 (CAS CATO-C4X-246646)
- Donepezil Open-Ring Hydroxy Acid (Na Salt) (CAS CATO-C4X-103971)
- 2-Amino-N-(4-chlorophenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 69438-16-0)
- 8-Chloro-9H-pyrido[2,3-b]indole (CAS 74896-09-6)
- Iridium(1+), [4,4′-bis(trifluoromethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-difluoro-2-(5-fluoro-2-pyridinyl-κN)phenyl-κC]-, hexafluorophosphate(1-) (1:1) (CAS 2229858-25-5)
- 1-[3-(aminomethyl)phenyl]ethan-1-one hydrochloride (CAS 149889-64-5)
- Methyl 6-amino-5-cyano-4-(4-fluorophenyl)-2-(2-methoxy-2-oxoethyl)-4h-pyran-3-carboxylate (CAS 371956-08-0)
- 3-Amino-2-chloroisonicotinonitrile (CAS 342899-37-0)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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