(2-Chloro-5-nitrophenyl)hydrazine CAS 96701-59-6
| CAS No. | 96701-59-6 |
| Molecular Formula | C6H6ClN3O2 |
| Molecular Weight | 187.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 187.58 g/mol gives (2-Chloro-5-nitrophenyl)hydrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2-Chloro-5-nitrophenyl)hydrazine (CAS 96701-59-6) is a high-purity analytical reference standard with the molecular formula C6H6ClN3O2 and a molecular weight of 187.58 g/mol.
The molecular framework of (2-Chloro-5-nitrophenyl)hydrazine (C6H6ClN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-Chloro-5-nitrophenyl)hydrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O2 |
| Molecular Weight | 187.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- N-(6-Chloro-3-oxo-2,3-dihydropyridazin-4-yl)acetamide (CAS 100367-79-1)
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Recommended Standards
- (2-chloro-4-nitrophenyl)hydrazine (CAS 55950-68-0)
- (2-Chloro-5-nitrophenyl)methanol (CAS 80866-80-4)
- (2-chloro-3-nitrophenyl)methanol (CAS 89639-98-5)
- (3-Chloro-2-nitrophenyl)methanol (CAS 77158-86-2)
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