Cefuroxime Sodium EP Impurity I(Ammonium Salt) CAS 97148-39-5
| CAS No. | 97148-39-5 |
| Molecular Formula | C7H6NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cefuroxime Sodium EP Impurity I(Ammonium Salt) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Cefuroxime Sodium EP Impurity I(Ammonium Salt) (CAS 97148-39-5), a pharmacopoeial impurity reference standard (molecular formula C7H6NO4H4N, MW 186.17 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cefuroxime Sodium EP Impurity I(Ammonium Salt) (C7H6NO4H4N) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H6NO4 H4N |
| Molecular Weight | 186.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
Related Cefuroxime Standards
- Cefuroxime Open-ring Impurity 44 (CAS 1177709-12-4)
- Di(cefuroxime Ethyl) Ether (CAS 1202925-10-7)
- Cefuroxime Axetil EP Impurity A (CAS 123458-61-7)
- Cefuroxime Axetil Impurity 5 (CAS 136235-54-6)
- Cefuroxime Impurity 33 (CAS 1467-70-5)
- Cefuroxime Impurity 36 (CAS 15690-38-7)
- Cefuroxime-d3 (CAS 1803240-98-3)
- Cefuroxime Impurity 51 (CAS 213912-35-7)
Recommended Standards
- Relugolix Impurity 21 (CAS CATO-C4X-242921)
- Hydrochlorothiazide Impurity 27 (CAS CATO-C4X-117727)
- Amitraz Impurity 1 (CAS 16596-04-6)
- trans-3,4-bis(iodomethyl)-1,1-dimethyl-silolane (CAS 1334313-86-8)
- 1-Phenyl-2-[-pyrrolidin-2-yl]ethan-1-ol (CAS 134877-26-2)
- (R)-N-cyclopentylidene-2-methylpropane-2-sulfinamide (CAS 891782-29-9)
- Topiramate Impurity 22 (CAS CATO-C4X-176822)
- Ethyl 3-(4-morpholinyl)-1-benzothiophene-2-carboxylate 1,1-dioxide (CAS 924859-09-6)
- 3-(4-ethoxyphenyl)-2-methylpropan-1-amine hydrochloride (CAS 1909317-55-0)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
Why CATO?
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