Momelotinib impurity 17 CAS 97604-01-8
| CAS No. | 97604-01-8 |
| Molecular Formula | C13H12N2O3 |
| Molecular Weight | 244.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Momelotinib impurity 17 (C13H12N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Momelotinib impurity 17 (CAS 97604-01-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12N2O3 and a molecular weight of 244.25 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Momelotinib impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12N2O3 |
| Molecular Weight | 244.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
Related Momelotinib Standards
- Momelotinib impurity 14 (CAS 2107522-02-9)
- Momelotinib impurity 15 (CAS CATO-C4X-337715)
- Momelotinib impurity 18 (CAS CATO-C4X-337718)
- Momelotinib impurity 10 (CAS CATO-C4X-337710)
- Momelotinib impurity 5 (CAS CATO-C4X-33775)
- Momelotinib impurity 16 (CAS CATO-C4X-337716)
- Momelotinib impurity 12 (CAS 97604-14-3)
- Momelotinib impurity 4 (CAS CATO-C4X-33774)
Recommended Standards
- 2-((2-Methoxyethyl)sulfonyl)benzoic acid (CAS 1016838-05-3)
- Etrasimod Impurity 48 (CAS CATO-C4X-321448)
- N-(3-Amino-4-methylphenyl)-4-fluorobenzamide (CAS 1016847-69-0)
- Finerenone Impurity 26 (CAS CATO-C4X-288026)
- Lansoprazole impurity 65 (CAS CATO-C4X-111365)
- Indacaterol Impurity 50 HCl (CAS 1384189-12-1(Free Base))
- Osimertinib Impurity 114 (CAS CATO-C4X-2045114)
- 5-Chloro-N-hydroxypicolinimidoyl chloride (CAS 1009562-96-2)
- ethyl 2-[4-(hydroxymethyl)piperidin-1-yl]acetate (CAS 1094301-16-2)
- 2-Chloro-4-iodo-6-(trifluoromethyl)pyridin-3-amine (CAS 1279875-31-8)
- 2-Chloro-4-(4-fluorobicyclo[2.2.2]Octan-1-yl)pyrimidine (CAS 2201290-18-6)
- Fluralaner impurity 40 (CAS CATO-C4X-218040)
- Tert-butyl 4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)piperidine-1-carboxylate (CAS 1610377-23-5)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
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