Momelotinib impurity 4 CAS CATO-C4X-33774
| CAS No. | CATO-C4X-33774 |
| Molecular Formula | C13H9ClN4O |
| Molecular Weight | 272.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Momelotinib impurity 4 (CAS CATO-C4X-33774) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9ClN4O and a molecular weight of 272.69 g/mol.
The molecular framework of Momelotinib impurity 4 (C13H9ClN4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Momelotinib impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN4O |
| Molecular Weight | 272.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Momelotinib Standards
- Momelotinib impurity 12 (CAS 97604-14-3)
- Momelotinib impurity 5 (CAS CATO-C4X-33775)
- Momelotinib impurity 10 (CAS CATO-C4X-337710)
- Momelotinib impurity 14 (CAS 2107522-02-9)
- Momelotinib impurity 15 (CAS CATO-C4X-337715)
- Momelotinib impurity 17 (CAS 97604-01-8)
- Momelotinib impurity 18 (CAS CATO-C4X-337718)
- Momelotinib impurity 16 (CAS CATO-C4X-337716)
Recommended Standards
- N-Nitroso Moxonidine Impurity 7 (CAS CATO-C4X-27817)
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- Nimustine (CAS 42471-28-3)
- 4-Fluoro-3-methanesulfonylbenzene-1-sulfonyl chloride (CAS 1188525-46-3)
- Esmolol Impurity 64 (CAS CATO-C4X-189164)
- Sugammadex Impurity Org197339-1 (CAS 2379877-90-2)
- Apixaban Impurity 106 (CAS CATO-C4X-1088106)
- 4-(2-Aminooxazol-5-yl)benzonitrile (CAS 1934636-72-2)
- Cefoxitin Impurity 8 (CAS CATO-C4X-15788)
- 1-Boc-4-chloro-3-iodo-1H-indole (CAS 406170-08-9)
- N-(1-Phenyl-2-(pyridin-4-yl)ethyl)aniline (CAS 15856-53-8)
- 2-Amino-4-methyl-5-propylthiophene-3-carbonitrile (CAS 143586-81-6)
- 3-(4-(Diethylamino)phenyl)propanoic acid (CAS 138643-01-3)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com