Nintedanib Impurity 62 CAS 34539-21-4
| CAS No. | 34539-21-4 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Nintedanib Impurity 62 (C8H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 166.18 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Nintedanib Impurity 62 (CAS 34539-21-4), a pharmacopoeial impurity reference standard (molecular formula C8H10N2O2, MW 166.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 62 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 2 |
Related Nintedanib Standards
- Nintedanib Impurity 47 (CAS 119-63-1)
- Nintedanib Impurity 68 (CAS 2840-28-0)
- Nintedanib Impurity 73 (CAS 54699-92-2)
- Nintedanib Impurity 34 (CAS 334952-09-9)
- Nintedanib Impurity 19 (CAS 1125-88-8)
- Nintedanib Impurity 160 (CAS 7207-35-4)
- Nintedanib Impurity 38 (CAS 58378-33-9)
- Nintedanib Impurity 42 (CAS 2186-92-7)
Recommended Standards
- Pazopanib Impurity 59 (CAS CATO-C4X-172559)
- Nikethamide Impurity 3 (CAS 68254-63-7)
- Pazopanib Impurity 29 (CAS 20191-74-6)
- Acipimox Impurity 14 (CAS 98006-89-4)
- Metaraminol Impurity 72 (CAS CATO-C4X-225272)
- Sitagliptin Impurity 80 (CAS 220199-85-9)
- Formoterol Impurity 67 (CAS 871266-45-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com