| CAS No. | 98027-36-2 |
| Molecular Formula | C5H5ClN2O |
| Molecular Weight | 144.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 144.56 g/mol gives 3-Amino-5-chloropyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Amino-5-chloropyridin-2(1H)-one (CAS 98027-36-2), a certified reference material (molecular formula C5H5ClN2O, MW 144.56 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-5-chloropyridin-2(1H)-one (C5H5ClN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-5-chloropyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C5H5ClN2O |
| Molecular Weight | 144.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |