3-Amino-5-chloropyridin-2(1H)-one CAS 98027-36-2

Purity 97%+In StockPharmaceutical Standards
CAS No.98027-36-2
Molecular FormulaC5H5ClN2O
Molecular Weight144.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Amino-5-chloropyridin-2(1H)-one CAS 98027-36-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 144.56 g/mol gives 3-Amino-5-chloropyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-Amino-5-chloropyridin-2(1H)-one (CAS 98027-36-2), a certified reference material (molecular formula C5H5ClN2O, MW 144.56 g/mol) for analytical method development and quality control.

The molecular framework of 3-Amino-5-chloropyridin-2(1H)-one (C5H5ClN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Amino-5-chloropyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H5ClN2O
Molecular Weight144.56 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms2

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