4-Amino-2-chloropyrimidine-5-carboxamide CAS 98027-38-4
| CAS No. | 98027-38-4 |
| Molecular Formula | C5H5ClN4O |
| Molecular Weight | 172.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Amino-2-chloropyrimidine-5-carboxamide (CAS 98027-38-4), a certified reference material (molecular formula C5H5ClN4O, MW 172.57 g/mol) for analytical method development and quality control.
Structurally, 4-Amino-2-chloropyrimidine-5-carboxamide (C5H5ClN4O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 172.57 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN4O |
| Molecular Weight | 172.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 6-Amino-3-chloropicolinic acid (CAS 1020917-27-4)
- 5-Amino-4-chloropicolinic acid (CAS 1060804-26-3)
- 6-Amino-4-chloropicolinic acid (CAS 1060808-93-6)
- 6-Amino-4-chloronicotinic Acid (CAS 1060808-94-7)
- 6-Amino-2-chloronicotinic acid (CAS 1060811-66-6)
- 3-Amino-5-chloroisonicotinic acid (CAS 1256785-41-7)
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Recommended Standards
- 4-Acetyl-5-chloropyridazin-3(2H)-one (CAS 2820002-77-3)
- 4-Amino-3-chloropicolinic acid (CAS 76165-18-9)
- 3-Chloro-6-methylpyridazine-4-carboxylic acid (CAS 914637-40-4)
- 4-amino-5-chloronicotinic acid (CAS 52834-09-0)
- 5-Bromo-7-fluoro-2-naphthaldehyde (CAS 1632077-32-7)
- Methyl 3-(N-(p-tolyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 899977-35-6)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one (CAS 1219131-64-2)
- 2-(4-Bromophenoxy)nicotinonitrile (CAS 82523-99-7)
- Methyl 2-amino-2-(1,4-dioxaspiro[4.5]decan-8-yl)acetate hydrochloride (CAS 1384264-14-5)
- Tepotinib impurity 30 (CAS CATO-C4X-337430)
- 2,4,6-Triisopropylbenzoic Acid (CAS 49623-71-4)
- 4-Thiazolecarboxylic acid, 5-(4-morpholinyl)-, ethyl ester (CAS 2070857-39-3)
- 4-Chloro-2-(3-methoxybenzyl)benzaldehyde (CAS 2699792-37-3)
- Peptide Impurity (CAS CATO-CPTD788810)
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