4-Chloro-6-methylpicolinonitrile CAS 98141-38-9
| CAS No. | 98141-38-9 |
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 153.57 g/mol gives 4-Chloro-6-methylpicolinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-6-methylpicolinonitrile (CAS 98141-38-9), molecular formula C6H4ClN3 and molecular weight 153.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-6-methylpicolinonitrile (C6H4ClN3) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- 2-(3-(Hydroxymethyl)piperidin-1-yl)propanoic acid (CAS 1218591-94-6)
- 5-(Dichloromethyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole (CAS 905107-65-5)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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