4-Chloro-6-methylpicolinaldehyde CAS 98273-77-9
| CAS No. | 98273-77-9 |
| Molecular Formula | C7H6ClNO |
| Molecular Weight | 155.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-6-methylpicolinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-6-methylpicolinaldehyde (CAS 98273-77-9) is a high-purity analytical reference standard with the molecular formula C7H6ClNO and a molecular weight of 155.58 g/mol.
The molecular framework of 4-Chloro-6-methylpicolinaldehyde (C7H6ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO |
| Molecular Weight | 155.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-(4-Chloro-1h-pyrazol-1-yl)propanenitrile (CAS 1001500-05-5)
- 4-Chloro-5-methylpicolinaldehyde (CAS 1060801-47-9)
- 2-Chloro-5-methylisonicotinaldehyde (CAS 1060801-49-1)
- 4-Chloro-5-methylnicotinaldehyde (CAS 1060801-51-5)
- 6-Chloro-4-methylpicolinaldehyde (CAS 1060804-70-7)
- 4-Chloro-6-methylnicotinaldehyde (CAS 1060805-86-8)
- 4-Chloro-2-methylnicotinaldehyde (CAS 1060805-88-0)
- 3-Chloro-6-methylpicolinaldehyde (CAS 1060810-01-6)
Recommended Standards
- 4-Chloro-3-methylpicolinaldehyde (CAS 59886-86-1)
- 4-Chlorobenzenecarbaldehyde oxime (CAS 3848-36-0)
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- 4-Chloropicolinimidamide (CAS 760173-28-2)
- N-(4-(3-(4-Fluorophenyl)ureido)cyclohexyl)benzamide (CAS 1956318-69-6)
- 3-(2-Aminoethyl)-1H-indol-6-ol (CAS 443-31-2)
- 2-(TERT-BUTYL)PHENYL ISOCYANATE (CAS 56309-60-5)
- 1-Cyclopentyl-3-methyl-1h-pyrazole-5-carbaldehyde (CAS 1245808-39-2)
- Cloxacillin Sodium Impurity 6 (CAS 83817-50-9)
- 4-Methylpyridine-2-carbothioamide (CAS 16225-37-9)
- 5-tert-butylpiperidin-2-one (CAS 65970-69-6)
- N,N-Dimethyl-2-nitropyridin-3-amine (CAS 36100-38-6)
- 5-amino-pyridin-2-ol (CAS 33630-94-3)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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