Milrinone Impurity 3 CAS 98293-81-3
| CAS No. | 98293-81-3 |
| Molecular Formula | C12H7N3O3 |
| Molecular Weight | 241.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Milrinone Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Milrinone Impurity 3 (CAS 98293-81-3, C12H7N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7N3O3 |
| Molecular Weight | 241.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
Related Milrinone Standards
- Milrinone Impurity 4 (CAS CATO-C4X-10914)
- Milrinone Impurity 6 (CAS 1443528-66-2)
- Milrinone Impurity 33 (CAS CATO-C4X-109133)
- Milrinone Impurity 32 (CAS CATO-C4X-109132)
- Milrinone impurity 42 (CAS CATO-C4X-109142)
- Milrinone Impurity 13 (CAS 80047-38-7)
- Milrinone Impurity 26 (CAS CATO-C4X-109126)
- Milrinone Impurity 14 (CAS CATO-C4X-109114)
Recommended Standards
- Methyl 4,5-Dimethoxy-2-nitrobenzoate (CAS 26791-93-5)
- Azacitidine Impurity 72 (CAS 4603-72-9)
- Methyl 3,6-Dimethoxy-2-nitrobenzoate, 97% (CAS 327163-76-8)
- Opicapone impurity 65 (CAS 64095-07-4)
- Venetoclax Impurity 63 (CAS CATO-C4X-249563)
- Tenofovir Alafenamide Impurity 5 (CAS 2055343-42-3)
- Lifitegrast Impurity 73 (CAS 2641788-18-1)
- Pentafluorothiophenol (CAS 771-62-0)
- 3-Chloro-N-(6-ethoxypyrimidin-4-yl)-4-fluorobenzenesulfonamide (CAS 1396862-23-9)
- 2-(Furan-2-yl)succinic acid (CAS 90111-44-7)
- 4-Fluorophthalazin-1-amine (CAS 2060049-41-2)
- Ethyl 6-oxodecanoate (CAS 4144-61-0)
- 2-(2-Amino-5-methylphenoxy)-N,N-dimethylacetamide hydrochloride (CAS 1208688-25-8)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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