Azacitidine Impurity 72 CAS 4603-72-9
| CAS No. | 4603-72-9 |
| Molecular Formula | C9H11N3O5 |
| Molecular Weight | 241.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Azacitidine Impurity 72 (CAS 4603-72-9), a pharmacopoeial impurity reference standard (molecular formula C9H11N3O5, MW 241.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Azacitidine Impurity 72 (C9H11N3O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11N3O5 |
| Molecular Weight | 241.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
Related Azacitidine Standards
- Azacitidine Impurity 28 (CAS 3530-56-1)
- Azacitidine Impurity 29 (CAS 26524-60-7)
- Azacitidine Impurity 43 (CAS 13913-16-1)
- Azacitidine Impurity 52 (CAS 77172-20-4)
- Azacitidine Impurity 53 (CAS 27921-78-4)
- Azacitidine Impurity 54 (CAS 16033-23-1)
- Azacitidine Impurity 56 (CAS 154568-81-7)
- Azacitidine Impurity 57 (CAS 16110-07-9)
Recommended Standards
- Milrinone Impurity 3 (CAS 98293-81-3)
- Opicapone impurity 65 (CAS 64095-07-4)
- Methyl 4,5-Dimethoxy-2-nitrobenzoate (CAS 26791-93-5)
- 1-(3-(Trifluoromethyl)benzyl)-1H-pyrazol-4-amine (CAS 1002033-51-3)
- Ceftolozane Impurity 44 (CAS CATO-C4X-240644)
- Metoprolol Impurity 30 (CAS 56392-16-6)
- Vardenafil Impurity 41 (CAS CATO-C4X-101741)
- 6-Chloro-4-methanesulfonyl-N-[(3-methoxyphenyl)methyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide (CAS 866142-58-7)
- Molnupiravir Impurity 10 (CAS CATO-C4X-249010)
- (S)-Methyl 2-amino-3-cyclopropylpropanoate hydrochloride (CAS 206438-31-5)
- 4-Chloro-6-(difluoromethoxy)-2-methylquinoline (CAS 1156276-49-1)
- Lopinavir EP Impurity A (CAS 192726-05-9)
- N-Thiomorpholinyl 4-bromobenzenesulfonamide (CAS 223555-81-5)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com