Halobetasol CAS 98651-66-2
| CAS No. | 98651-66-2 |
| Molecular Formula | C22H27ClF2O4 |
| Molecular Weight | 428.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Halobetasol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Halobetasol (CAS 98651-66-2), a certified reference material (molecular formula C22H27ClF2O4, MW 428.90 g/mol) for analytical method development and quality control.
Halobetasol (C22H27ClF2O4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H27ClF2O4 |
| Molecular Weight | 428.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
Related Halobetasol Standards
- Halobetasol Propionate Impurity 14 (CAS CATO-C4X-331414)
- Halobetasol Impurity 8 (CAS CATO-C4X-33148)
- Halobetasol Impurity 7 (CAS 32232-54-5)
- Halobetasol Impurity 13 (CAS CATO-C4X-331413)
- Halobetasol Impurity 9 (CAS CATO-C4X-33149)
- Halobetasol Impurity 10 (CAS CATO-C4X-331410)
- Halobetasol Impurity 3 (CAS 181527-42-4)
- Halobetasol Impurity 4 (CAS CATO-C4X-33144)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com