Lomefloxacin Impurity 2 CAS 99726-76-8
| CAS No. | 99726-76-8 |
| Molecular Formula | C16H17F2N3O3 |
| Molecular Weight | 337.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lomefloxacin Impurity 2.
Lomefloxacin Impurity 2 (CAS 99726-76-8) is a certified pharmaceutical impurity reference standard with the molecular formula C16H17F2N3O3 and a molecular weight of 337.32 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Lomefloxacin Impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lomefloxacin Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17F2N3O3 |
| Molecular Weight | 337.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Lomefloxacin Standards
- Lomefloxacin Impurity 19 (CAS CATO-C4X-207319)
- Lomefloxacin Impurity 8 (CAS 195259-12-2)
- Lomefloxacin Impurity N1 (CAS 195259-11-1)
- Lomefloxacin Impurity 11 (CAS CATO-C4X-207311)
- Lomefloxacin Impurity 18 (CAS CATO-C4X-207318)
- Lomefloxacin (CAS 98079-51-7)
- Lomefloxacin-D5 (CAS CATO-CCAD303929)
- Lomefloxacin Impurity 9 (CAS 183235-15-6)
Recommended Standards
- Posaconazole impurity 227 (CAS CATO-C4X-1208227)
- Perampanel Impurity 31 (CAS CATO-C4X-243031)
- Moxifloxacin Impurity 74 (CAS CATO-C4X-107474)
- Orbifloxacin Impurity 3 (CAS CATO-C4X-25673)
- Pemafibrate Impurity 12 (CAS CATO-C4X-290312)
- Testosterone Enantate EP Impurity F (CAS CATO-C4X-243251)
- Miglitol Impurity 19 (CAS 78614-47-8)
- 2-(4-bromo-2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride (CAS 85792-59-2)
- 1-Cyclopentyl-1-(pyridin-3-yl)methanamine (CAS 1178320-32-5)
- Flamprop-M-isopropyl Solution (CAS 57973-67-8)
- 4-Chloro-3-cyclopropylpyridine hydrochloride (CAS 1998216-32-2)
- 4-(Benzylamino)-2-(methylthio)pyrimidine-5-carboxamide (CAS 919486-26-3)
- N-[(4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl)carbonyl]-N'-(4-fluorophenyl)urea (CAS 650615-82-0)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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