Lomefloxacin Impurity 8 CAS 195259-12-2
| CAS No. | 195259-12-2 |
| Molecular Formula | C16H16FN3O4 |
| Molecular Weight | 333.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Lomefloxacin Impurity 8 (CAS 195259-12-2, C16H16FN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H16FN3O4, Lomefloxacin Impurity 8 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 333.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Lomefloxacin Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16FN3O4 |
| Molecular Weight | 333.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Lomefloxacin Standards
- Lomefloxacin Impurity N1 (CAS 195259-11-1)
- Lomefloxacin Impurity 11 (CAS CATO-C4X-207311)
- Lomefloxacin Impurity 19 (CAS CATO-C4X-207319)
- Lomefloxacin Impurity 2 (CAS 99726-76-8)
- Lomefloxacin Impurity 18 (CAS CATO-C4X-207318)
- Lomefloxacin (CAS 98079-51-7)
- Lomefloxacin-D5 (CAS CATO-CCAD303929)
- Lomefloxacin Impurity 9 (CAS 183235-15-6)
Recommended Standards
- Norfloxacin Impurity 19 (CAS 74011-42-0)
- Upadacitinib Impurity 1 (CAS CATO-C4X-24051)
- Retigabine impurity 13 (CAS CATO-C4X-13153)
- 1-(2-Fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-00-4)
- Pranoprofen Impurity 5 (CAS 145986-74-9)
- Phloroglucinol Impurity 68 (CAS CATO-C4X-221768)
- Doxazosin EP Impurity G (CAS 60547-97-9)
- 4-Bromo-1H-pyrazol-1-ol (CAS 87844-44-8)
- 2-(tert-Butoxy)-4-chlorophenol (CAS 1243288-82-5)
- 5-(4-Chlorobenzyl)-2-(piperidin-3-yl)oxazole (CAS 1785761-50-3)
- 1-Bromo-5-iodopentane (CAS 88962-86-1)
- 6,7-Dimethyl-1H-pyrrolo[3,2-b]pyridine (CAS 1190320-01-4)
- 2-(Pyridin-4-ylmethyl)piperazine (CAS 907972-04-7)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com