2-Chloro-4-(4-isopropylphenyl)thiazole CAS 99797-29-2
| CAS No. | 99797-29-2 |
| Molecular Formula | C12H12ClNS |
| Molecular Weight | 237.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-(4-isopropylphenyl)thiazole (CAS 99797-29-2), molecular formula C12H12ClNS and molecular weight 237.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4-(4-isopropylphenyl)thiazole (C12H12ClNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-(4-isopropylphenyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNS |
| Molecular Weight | 237.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1019535-48-8)
- 3-Chloro-N-(1-(thiophen-2-yl)ethyl)aniline (CAS 1019541-12-8)
- 4-Chloro-N-(1-(thiophen-2-yl)ethyl)aniline (CAS 1019619-42-1)
- 5-Chloro-2-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1019631-23-2)
- 2-Chloro-4-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1039901-30-8)
- 2-Chloro-4-methyl-N-(thiophen-2-ylmethyl)aniline (CAS 1040056-01-6)
- 4-Chloro-2-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1040320-47-5)
- 4-Chloro-6-(isopropylthio)quinoline (CAS 1912423-48-3)
Recommended Standards
- 3-Chloro-4-methyl-N-(thiophen-2-ylmethyl)aniline (CAS 940367-35-1)
- Quinoline-8-sulfonyl chloride (CAS 18704-37-5)
- 4-(Chloromethyl)-2-(4-ethylphenyl)thiazole (CAS 900641-46-5)
- 1-methylindole-2-sulfonyl chloride (CAS 184039-88-1)
- 4-Bromo-6-methoxyquinolin-3-amine (CAS 872714-60-8)
- 2-(Methylamino)-2-(4-(trifluoromethoxy)phenyl)acetic acid (CAS 1218157-85-7)
- N-(2-((tert-Butyldimethylsilyl)oxy)ethylidene)-2-methylpropane-2-sulfinamide (CAS 918413-70-4)
- (S)-8-(trifluoromethyl)chroman-4-amine hydrochloride (CAS 1392219-36-1)
- 4-(3,5-Dichlorophenyl)oxazolidin-2-one (CAS 1496336-32-3)
- 1-((4-Bromophenyl)sulfonyl)-1H-indole (CAS 170432-90-3)
- 5-Bromo-6-fluoro-1-methyl-1H-benzimidazole (CAS 1311197-80-4)
- 4-(Chloromethyl)-6-methoxy-3,3'-bipyridine (CAS 1227589-86-7)
- 2-(2,4-Difluorophenyl)-4,4-dimethyl-3-oxopentanenitrile (CAS 1378595-85-7)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
Why CATO?
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