2-Chloro-5-(methylsulfonyl)pyridine CAS 99903-01-2
| CAS No. | 99903-01-2 |
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-(methylsulfonyl)pyridine.
CATO supplies 2-Chloro-5-(methylsulfonyl)pyridine (CAS 99903-01-2), a certified reference material (molecular formula C6H6ClNO2S, MW 191.64 g/mol) for analytical method development and quality control.
2-Chloro-5-(methylsulfonyl)pyridine (C6H6ClNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-(methylsulfonyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-(methylsulfonyl)pyridine (CAS 100560-78-9)
- 2-Chloro-N-(1,3,4-thiadiazol-2-yl)propanamide (CAS 1019456-17-7)
- 5-Chloro-2-(1,3-dioxolan-2-yl)-1,3-thiazole (CAS 1080061-38-6)
- 2-Chloro-5-ethyl-1,3-thiazole-4-carboxylic acid (CAS 1194374-29-2)
- 2-Chloro-4-ethylthiazole-5-carboxylic acid (CAS 1194374-35-0)
- 4-Chloro-3-(methylsulfonyl)pyridine (CAS 1346535-76-9)
- Methyl 2-chloro-5-methylthiazole-4-carboxylate (CAS 1378819-18-1)
- 2-Chloro-5-methylthiazole-4-carbohydrazide (CAS 1379326-16-5)
Recommended Standards
- 2-Chloro-4-methoxy-6-(methylthio)-1,3,5-triazine (CAS 4407-44-7)
- 2-Chloro-5-(S-methylsulfonimidoyl)pyrimidine (CAS 2743442-76-2)
- 2-Chloro-4-(methylsulfonyl)pyridine (CAS 99903-03-4)
- 2-Chloro-6-(methylsulfonyl)pyridine (CAS 87512-29-6)
- N-[3-(3-Amino-4-nitrophenoxy)phenyl]-3-(trifluoromethyl)benzene-1-sulfonamide (CAS 1400989-38-9)
- 4-(4-Carboxy-3-fluorophenyl)phenol (CAS 168100-28-5)
- N-((3aR,4S,6R,6aS)-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)hydroxylamine (CAS 1226812-52-7)
- 5-Bromo-N-ethyl-2-isobutoxynicotinamide (CAS 1707568-43-1)
- 1-((2,3-Dihydro-1H-inden-5-yl)sulfonyl)piperazine (CAS 794582-39-1)
- 5-(4-Iodophenoxymethyl)furan-2-carbaldehyde (CAS 832738-06-4)
- tert-Butyl prop-2-yn-1-yl(2-(trifluoromethyl)pyridin-4-yl)carbamate (CAS 2408199-30-2)
- Sorbic Acid Impurity 2 (CAS 14202-27-8)
- 2-(1H-1,2,3-Triazol-1-yl)thiazole (CAS 179753-59-4)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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