New Drug Impurity 63 D5 CAS CATO-C3D-262963
| CAS No. | CATO-C3D-262963 |
| Molecular Formula | - |
| Molecular Weight | 627.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, New Drug Impurity 63 D5 (CAS CATO-C3D-262963, C34H45D5N6O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, New Drug Impurity 63 D5 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 627.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H45D5N6O5 |
| Molecular Weight | 627.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Recommended Standards
- Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (CAS 187393-00-6)
- 2-[1,3-Bis(dicyclohexylphosphino)-1H-inden-2-yl]-N,N-dimethylbenzenamine (CAS 1651150-93-4)
- N-(t-Butyl ester-PEG3)-N-bis(PEG3-amine) (CAS 2183440-29-9)
- [S(R)]-N-[(1S)-1-[3',5'-Bis(1,1-dimethylethyl)-4'-methoxy[1,1'-biphenyl]-2-yl]-2-(diphenylphosphino)ethyl]-2-methyl-2-propanesulfinamide (CAS 1936438-26-4)
- Iopamidol Impurity 49 (CAS CATO-C4X-145049)
- Promethazine Impurity 27 (CAS 1209-66-1)
- Amisulpride Impurity 19 (CAS 483304-03-6)
- 1,1,2,2-Tetrafluoro-3-butanone (CAS 679-97-0)
- N-Butyl-2-ethyl-N-(4-methyloxazol-2-yl)butanamide (CAS 57067-78-4)
- 3-Chloro-4-(3,4-dichlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5,9,11-pentaene (CAS 866137-13-5)
- (2R,6S,6aS)-6-triphenylsilyloxy-1,2,4,5,6,6a-hexahydropentalen-2-ol (CAS 2410639-39-1)
- Methyl 5-((5-fluoro-2-nitrophenoxy)methyl)furan-2-carboxylate (CAS 832739-23-8)
- Ganglioside GM1, Asialo (CAS 71012-19-6)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com