Aripiprazole Impurity 54 CAS CATO-C4X-100854
| CAS No. | CATO-C4X-100854 |
| Molecular Formula | C17H23N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Aripiprazole Impurity 54 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Aripiprazole Impurity 54 (CAS CATO-C4X-100854, C17H23N3O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Aripiprazole Impurity 54 (C17H23N3O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Aripiprazole Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H23N3O2 2*HCl |
| Molecular Weight | 337.85 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Aripiprazole Standards
- Aripiprazole HCl (CAS 1026778-41-5)
- Aripiprazole Impurity N17 (CAS 1076199-56-8)
- Aripiprazole-d8 (CAS 1089115-04-7)
- Aripiprazole-d8 (CAS 1089115-06-9)
- Aripiprazole Impurity 32 (CAS 1147995-98-9)
- Aripiprazole-d (CAS 1185116-86-2)
- Aripiprazole EP Impurity B HCL (CAS 119532-26-2)
- Aripiprazole Impurity 8 (CAS 120004-79-7)
Recommended Standards
- Omeprazole Impurity 44 (CAS 69818-23-1)
- Fasudil Impurity 33 (CAS CATO-C4X-136533)
- Brexpiprazole Impurity 158 (CAS CATO-C4X-1131158)
- 2-(2-Fluoro-4-iodopyridin-3-yl)ethan-1-ol (CAS 1620011-25-7)
- Cyanoacetic Acid (CAS 372-09-8)
- 2-((Tert-butoxycarbonyl)(methyl)amino)-3-methoxy-2-methylpropanoic acid (CAS 1490050-23-1)
- 1-(1-(4-Bromophenyl)ethyl)-4-methylpiperazine (CAS 1704069-15-7)
- Fluconazole Impurity 44 (CAS 6086-21-1)
- H-Asn-OtBu (CAS 25456-86-4)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
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