Baclofen impurity 28 CAS CATO-C4X-101228
| CAS No. | CATO-C4X-101228 |
| Molecular Formula | C14H14ClNO3 |
| Molecular Weight | 279.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Baclofen impurity 28 (C14H14ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Baclofen impurity 28 (CAS CATO-C4X-101228) is a certified pharmaceutical impurity reference standard with the molecular formula C14H14ClNO3 and a molecular weight of 279.72 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Baclofen impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14ClNO3 |
| Molecular Weight | 279.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen impurity 30 (CAS CATO-C4X-101230)
- Baclofen impurity 31 (CAS CATO-C4X-101231)
- Baclofen impurity 32 (CAS CATO-C4X-101232)
- Baclofen Impurity 39 (CAS CATO-C4X-101239)
- Baclofen Impurity 35 (CAS CATO-C4X-101235)
- Baclofen Impurity 66 (CAS CATO-C4X-101266)
- Baclofen impurity 45 (CAS CATO-C4X-101245)
- Baclofen Impurity 63 (CAS CATO-C4X-101263)
Recommended Standards
- Trans-4-(3-chloro-4-cyano-phenoxy)cyclohexanecarboxylicacid (CAS 2222114-60-3)
- tert-Butyl 5-chloro-3-formyl-1H-indole-1-carboxylate (CAS 314248-57-2)
- Domperidone EP Impurity B (CAS 1346598-11-5)
- Tert-butyl 4-chloro-3-formyl-1H-indole-1-carboxylate (CAS 914349-00-1)
- Etomidate impurity 57 (CAS CATO-C4X-188457)
- Dapagliflozin Impurity 144 (CAS 1408245-02-2)
- Bumetanide Impurity 49 (CAS CATO-C4X-198649)
- Methyl 3-hydroxy-5-oxocyclohex-3-enecarboxylate (CAS 135365-38-7)
- 1-(2-Chloro-5-fluoropyridin-4-yl)ethanone (CAS 736990-31-1)
- Afoxolaner Impurity 14 (CAS 1125726-30-8)
- Tris(2-cyclohexylethyl)(phenyl)silane (CAS 18758-76-4)
- 2-(Cbz-amino)propanamide (CAS 2503-29-9)
- 8-(1-Butoxyvinyl)[1,5]naphthyridin-2-yl methyl ether (CAS 1370553-19-7)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com