Bicalutamide Impurity 37 CAS CATO-C4X-101337
| CAS No. | CATO-C4X-101337 |
| Molecular Formula | C24H18F5NO3S2 |
| Molecular Weight | 527.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bicalutamide Impurity 37.
As a process- or degradation-related impurity, Bicalutamide Impurity 37 (CAS CATO-C4X-101337, C24H18F5NO3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Bicalutamide Impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 527.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H18F5NO3S2 |
| Molecular Weight | 527.53 g/mol |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Bicalutamide Standards
- Bicalutamide Impurity 35 (CAS CATO-C4X-101335)
- Bicalutamide Impurity 27 (CAS 937802-59-0)
- Bicalutamide EP Impurity L (CAS 2711603-77-7)
- Bicalutamide EP Impurity K (CAS CATO-C4X-101317)
- Bicalutamide EP Impurity K (CAS 2711603-77-7(racemate))
- Bicalutamide Glucoronide (CAS 151262-59-8)
- Bicalutamide Impurity 30 (CAS CATO-C4X-101330)
- Bicalutamide Impurity 26 (CAS 1217519-01-1)
Recommended Standards
- 7β-[(Z)-2-(2-Aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido]-3-acetoxymethyl-3-cephem-4-carboxylic Acid (CAS 73443-60-4)
- Ceftazidime Impurity 59 (CAS CATO-C4X-121259)
- N-(2-(6-(((Benzyloxy)carbonyl)amino)-9H-purin-9-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine (CAS 149376-69-2)
- epi-Daunorubicin (CAS 57918-24-8)
- Fluvoxamine impurity 41 (CAS CATO-C4X-195141)
- Lotilaner Impurity 3 (CAS CATO-C4X-32563)
- Cefpirome Impurity 41 (CAS CATO-C4X-120741)
- Coenzyme Q10-d6 (CAS 110971-02-3)
- 5-Chloro-2-(4-methylphenyl)-1H-imidazole-4-carbaldehyde (CAS 74207-83-3)
- 4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic Acid-d7 (CAS 1216407-26-9)
- 2-(3-Amino-1h-pyrazol-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1247340-56-2)
- 5-Chloro-2-fluoro-3-(4-fluorophenyl)pyridine (CAS 1214389-22-6)
- 2-Methoxy-n-(4-phenyl-1,3-thiazol-2-yl)acetamide (CAS 132214-37-0)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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