Bicalutamide Impurity 35 CAS CATO-C4X-101335
| CAS No. | CATO-C4X-101335 |
| Molecular Formula | C24H18F6N4O2 |
| Molecular Weight | 508.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Bicalutamide Impurity 35 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Bicalutamide Impurity 35 (CAS CATO-C4X-101335, C24H18F6N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H18F6N4O2, Bicalutamide Impurity 35 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 508.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H18F6N4O2 |
| Molecular Weight | 508.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Bicalutamide Standards
- Bicalutamide Impurity 37 (CAS CATO-C4X-101337)
- Bicalutamide Impurity 27 (CAS 937802-59-0)
- Bicalutamide Impurity 30 (CAS CATO-C4X-101330)
- (R)-Bicalutamide-d4 (CAS 1217826-87-3)
- (S)-Bicalutamide (CAS 113299-38-0)
- Bicalutamide impurity A (CAS 113299-40-4)
- Bicalutamide EP Impurity H (CAS 2512198-58-0)
- Bicalutamide EP Impurity B (CAS 1159977-36-2)
Recommended Standards
- Ethyl4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)-1h-pyrazole-3-carboxylate (CAS 2170134-91-3)
- Crizotinib Impurity 72 (CAS CATO-C4X-102572)
- ((2R,3S,5R)-5-(5-(1,4-Dimethoxy-3-methylnaphthalen-2-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 105785-92-0)
- Dasatinib impurity 63 (CAS CATO-C4X-160763)
- Salbutamol Impurity 68 (CAS 18910-63-9)
- Prucalopride Impurity 8 (CAS 1900715-98-1)
- Vincamine EP Impurity C (CAS 32790-09-3)
- (2-(1H-imidazol-1-yl)phenyl)methanamine dihydrochloride (CAS 1197227-61-4)
- 6-Amino-1-methyl-5,6,7,8-tetrahydroquinolin-2(1H)-one (CAS 1422142-23-1)
- 4-ethyl-2-fluoro-benzamide (CAS 1369809-97-1)
- 3,4-Dihydro-2H-benzo[b][1,4]oxazin-6-amine hydrochloride (CAS 207596-59-6)
- Methyl 2-(4-aminophenyl)-2-hydroxyacetate (CAS 182918-73-6)
- Ethyl 5-(pyridin-3-yl)-1,3,4-oxadiazole-2-carboxylate (CAS 89546-91-8)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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