Vonoprazan Impurity 184 CAS CATO-C4X-1020184
| CAS No. | CATO-C4X-1020184 |
| Molecular Formula | C23H18F2N2 |
| Molecular Weight | 360.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Vonoprazan Impurity 184 (CAS CATO-C4X-1020184, C23H18F2N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Vonoprazan Impurity 184 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H18F2N2 |
| Molecular Weight | 360.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Fumarate Impurity 79 (CAS CATO-C4X-102079)
- Vonoprazan Impurity 225 (CAS CATO-C4X-1020225)
- Vonoprazan Impurity 101 (CAS 1885094-62-1)
- Vonoprazan Impurity 168 (CAS CATO-C4X-1020168)
- Vonoprazan Impurity 211 (CAS CATO-C4X-1020211)
- Vonoprazan Impurity 240 (CAS CATO-C4X-1020240)
- Vonoprazan Impurity 273 (CAS CATO-C4X-1020273)
- Vonoprazan Impurity 282 (CAS CATO-C4X-1020282)
Recommended Standards
- 7789-47-1 P986675T8V Mercuric bromide Mercury bromide (HgBr2) Mercury dibromide Mercury(II) bromide (1:2) EINECS 232-169-3 HSDB 829 Mercuric dibromide UNII-P986675T8V (CAS 7789-47-1)
- Sculponeatin B (CAS 85287-60-1)
- Estriol Impurity 21 (CAS CATO-C4X-163721)
- N-Dihydrocinnamoylaminocaproic Acid N-Hydroxysuccinimide Ester (CAS 334616-48-7)
- Ranitidine EP Impurity I (CAS 207592-21-0)
- Lacosamide impurity 40 (CAS CATO-C4X-183040)
- Tirofiban Impurity 20 (CAS CATO-C4X-125420)
- 2-Amino-4-(2,5-difluorophenyl)butanoic acid (CAS 1260643-72-8)
- 2-amino-8-(pyridin-3-yl)-7,9-dioxa-1-thia-3-azaspiro[4.5]dec-2-en-4-one (CAS 312608-26-7)
- n-Isopropyl-2,6-dimethylmorpholine-4-sulfonamide (CAS 1378322-46-3)
- 3-(4-Chloro-3-methylphenoxy)-8-((dipropylamino)methyl)-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one (CAS 685861-44-3)
- n-((1,5-Dimethyl-1h-pyrazol-4-yl)methyl)-3-methylbutan-1-amine (CAS 1528672-64-1)
- (6-Bromo-[2,3'-bipyridin]-4-yl)boronic acid (CAS 2225173-56-6)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
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