Vonoprazan Impurity 8 CAS CATO-C4X-10208
| CAS No. | CATO-C4X-10208 |
| Molecular Formula | C16H9ClFN3O2S |
| Molecular Weight | 361.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Vonoprazan Impurity 8 (CAS CATO-C4X-10208) is a certified pharmaceutical impurity reference standard with the molecular formula C16H9ClFN3O2S and a molecular weight of 361.78 g/mol.
Structurally, Vonoprazan Impurity 8 (C16H9ClFN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 361.78 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H9ClFN3O2S |
| Molecular Weight | 361.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 168 (CAS CATO-C4X-1020168)
- Vonoprazan Impurity 211 (CAS CATO-C4X-1020211)
- Vonoprazan Impurity 240 (CAS CATO-C4X-1020240)
- Vonoprazan Impurity 273 (CAS CATO-C4X-1020273)
- Vonoprazan Impurity 282 (CAS CATO-C4X-1020282)
- Vonoprazan Fumarate Impurity 48 (CAS CATO-C4X-102048)
- Vonoprazan Impurity 67 (CAS CATO-C4X-102067)
- Vonoprazan Fumarate Impurity 75 (CAS CATO-C4X-102075)
Recommended Standards
- N-(5-chloro-2-morpholinophenyl)-3-nitrobenzamide (CAS 383146-61-0)
- Fenoxaprop-Ethyl (CAS 66441-23-4)
- N-(4-chloro-9,10-dioxo-9,10-dihydroanthracen-1-yl)benzamide (CAS 81-45-8)
- Fenoxaprop-P-ethyl (CAS 71283-80-2)
- Cimetidine EP Impurity A (CAS 52378-40-2)
- Iohexol impurity 40 (CAS CATO-C4X-166440)
- Mitoxantrone EP Impurity B (CAS 80189-44-2)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(3,4-dimethoxyphenyl)-3-hydroxy-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 488734-25-4)
- 1-((3,4-Dimethylphenyl)sulfonyl)piperazine (CAS 524711-31-7)
- (R)-(7-Benzyl-4,7-diazaspiro[2.5]octan-6-yl)methanol (CAS 1235577-03-3)
- (E)-4-(Benzylideneamino)benzonitrile (CAS 17224-21-4)
- Dibenzo[b,d]thiophen-4-yltriphenylsilane (CAS 18866-39-2)
- N-(4-Ethoxybenzo[d]thiazol-2-yl)acetamide (CAS 313661-90-4)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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