Carfilzomib Impurity 74 CAS CATO-C4X-102274
| CAS No. | CATO-C4X-102274 |
| Molecular Formula | C62H84N10O10 |
| Molecular Weight | 1129.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Carfilzomib Impurity 74 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Carfilzomib Impurity 74 (CAS CATO-C4X-102274, C62H84N10O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Carfilzomib Impurity 74 (C62H84N10O10) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carfilzomib Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C62H84N10O10 |
| Molecular Weight | 1129.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 10 |
Related Carfilzomib Standards
- Carfilzomib Impurity 51 (CAS CATO-C4X-102251)
- Carfilzomib Impurity 38 (Mixture of Diastereomers) (CAS CATO-C4X-102238)
- Carfilzomib Impurity 57 (CAS CATO-C4X-102257)
- Carfilzomib Impurity 60 (Mixture of Diastereomers) (CAS CATO-C4X-102260)
- Carfilzomib Impurity 40 (CAS CATO-C4X-102240)
- Carfilzomib Impurity 89 (CAS CATO-C4X-102289)
- Carfilzomib Impurity 93 (CAS CATO-C4X-102293)
- Carfilzomib Impurity 94 (CAS CATO-C4X-102294)
Recommended Standards
- 476647-30-0 PUBCHEM_71433817 DTXSID00849557 (CAS 476647-30-0)
- Hormaomycin (CAS 121548-21-8)
- 194874-06-1 (12R,13R)-12-Hydroxy-13-methyl-20-oxo-1-oxacycloicosa-8,10,14,16,18-pentaene-2,4,5-triyl DTXSID90849586 (CAS 194874-06-1)
- 1,4,8,11,15,18,22,25-octabutoxy-29<I>H</I>,31<I>H</I>-phthalocyanine (CAS 116453-73-7)
- Trelagliptin impurity 71 (CAS 2204313-60-8)
- Ceftriaxone Impurity 13 (CAS CATO-C4X-116313)
- Leuprorelin Impurity 45 (CAS CATO-C4X-182245)
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- 2-(Difluoromethoxy)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1402238-41-8)
- 1,6-Di(spiro[fluorene-9,9'-xanthen]-2-yl)pyrene (CAS 1246183-53-8)
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- N-(2,4-dibromophenyl)-2-morpholinoacetamide (CAS 866154-43-0)
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