Capecitabine Impurity 44 CAS CATO-C4X-102444
| CAS No. | CATO-C4X-102444 |
| Molecular Formula | C11H14FN3O5 |
| Molecular Weight | 287.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Capecitabine Impurity 44 (CAS CATO-C4X-102444) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14FN3O5 and a molecular weight of 287.24 g/mol.
The molecular framework of Capecitabine Impurity 44 (C11H14FN3O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Capecitabine Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14FN3O5 |
| Molecular Weight | 287.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Capecitabine Standards
- Capecitabine Impurity 43 (CAS CATO-C4X-102443)
- Capecitabine Impurity 17 (CAS 38838-05-0)
- Capecitabine Impurity 11 (CAS 111878-21-8)
- Capecitabine Impurity 37 (CAS CATO-C4X-102437)
- Capecitabine Impurity 12 (CAS 62211-93-2)
- Capecitabine Impurity 14 (CAS 76497-54-6)
- Capecitabine Impurity 41 (CAS CATO-C4X-102441)
- Capecitabine Impurity 55 (CAS CATO-C4X-102455)
Recommended Standards
- 1-(2-Fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1160246-27-4)
- 1-(4'-Bromobiphenyl-4-yl)ethan-1-one 1-[4-(4-bromophenyl)phenyl]ethanone 4'-(4-Bromophenyl)acetophenone 5731-01-1 (CAS 5731-01-1)
- N-(3-Nitrophenyl)-2-oxooxazolidine-3-sulfonamide (CAS 116943-61-4)
- 2-(4-Bromophenyl)imidazo[1,2-a]pyridine 2-(4-bromophenyl)H-imidazo[1,2-a]pyridine 34658-66-7 A21922 (CAS 34658-66-7)
- Capecitabine Impurity 48 (CAS CATO-C4X-102448)
- Rosuvastatin Impurity 146 (CAS 148809-28-3)
- Amifostine Impurity 2 (CAS 14653-77-1)
- 4-Fluoro-2-nitrophenylboronic acid (CAS 860034-00-0)
- 2-Chloro-5-cyclopropyl-7-methoxyquinazolin-4(3H)-one (CAS 601514-53-8)
- 3-methyl-1H-pyrrolo[2,3-c]pyridine (CAS 25796-95-6)
- (5E)-5-[(Furan-2-yl)methylidene]-2-[2-(2-hydroxyethyl)piperidin-1-yl]-4,5-dihydro-1,3-thiazol-4-one (CAS 866132-82-3)
- (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid (CAS 244132-27-2)
- 3-(Methylamino)-4-phenylbutanoic acid (CAS 60343-06-8)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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