Capecitabine Impurity 43 CAS CATO-C4X-102443
| CAS No. | CATO-C4X-102443 |
| Molecular Formula | C11H14FN3O5 |
| Molecular Weight | 287.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Capecitabine Impurity 43 (C11H14FN3O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Capecitabine Impurity 43 (CAS CATO-C4X-102443) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14FN3O5 and a molecular weight of 287.24 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Capecitabine Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14FN3O5 |
| Molecular Weight | 287.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Capecitabine Standards
- Capecitabine Impurity 44 (CAS CATO-C4X-102444)
- Capecitabine Impurity 17 (CAS 38838-05-0)
- Capecitabine Impurity 11 (CAS 111878-21-8)
- Capecitabine Impurity 37 (CAS CATO-C4X-102437)
- Capecitabine Impurity 12 (CAS 62211-93-2)
- Capecitabine Impurity 14 (CAS 76497-54-6)
- Capecitabine Impurity 41 (CAS CATO-C4X-102441)
- Capecitabine Impurity 55 (CAS CATO-C4X-102455)
Recommended Standards
- 1-(4'-Bromobiphenyl-4-yl)ethan-1-one 1-[4-(4-bromophenyl)phenyl]ethanone 4'-(4-Bromophenyl)acetophenone 5731-01-1 (CAS 5731-01-1)
- 2-(4-Bromophenyl)imidazo[1,2-a]pyridine 2-(4-bromophenyl)H-imidazo[1,2-a]pyridine 34658-66-7 A21922 (CAS 34658-66-7)
- 1-(2-Fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1160246-27-4)
- Methyl 7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 338778-27-1)
- Lapatinib Impurity 11 (CAS 231278-83-4)
- Venlafaxine Impurity 76 (CAS CATO-C4X-143476)
- Roxithromycin Impurity 14 (CAS CATO-C4X-130314)
- H-D-Thr(tBu)-OMe · HCl (CAS 115141-43-0)
- 2,4-Bis[(trimethylsilyl)oxy]benzoic Acid Trimethylsilyl EsterDISCONTINUED (CAS 10586-16-0)
- 1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321998-53-2)
- 1,3-Dihydrobenzo[c]thiophene-5-carbothioamide (CAS 1256483-70-1)
- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide (CAS 476483-85-9)
- 3-(3,5-Dimethylphenyl)-3-hydroxypropanenitrile (CAS 1538836-32-6)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
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