Crizotinib impurity 28 CAS CATO-C4X-102528
| CAS No. | CATO-C4X-102528 |
| Molecular Formula | C42H43Cl4FN10O2 |
| Molecular Weight | 880.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 880.67 g/mol gives Crizotinib impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Crizotinib impurity 28 (CAS CATO-C4X-102528) is a certified pharmaceutical impurity reference standard with the molecular formula C42H43Cl4FN10O2 and a molecular weight of 880.67 g/mol.
Crizotinib impurity 28 (C42H43Cl4FN10O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Crizotinib impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C42H43Cl4FN10O2 |
| Molecular Weight | 880.67 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 10 |
Related Crizotinib Standards
- Crizotinib Impurity 52 (CAS CATO-C4X-102552)
- Crizotinib Impurity 61 (CAS CATO-C4X-102561)
- Crizotinib impurity 26 (CAS CATO-C4X-102526)
- Crizotinib Impurity 50 (CAS CATO-C4X-102550)
- Crizotinib Impurity 53 (CAS CATO-C4X-102553)
- Crizotinib Impurity 21 (CAS 1428476-86-1)
- Crizotinib Impurity 01 (CAS 877399-51-4)
- Crizotinib Impurity 72 (CAS CATO-C4X-102572)
Recommended Standards
- (4,8-Bis(3-butylnonyl)benzo[1,2-b:4,5-b']dithiophene-2,6-diyl)bis(trimethylstannane) (CAS 1227363-47-4)
- Cyclotetrakis (1,4-Butylene Terephthalate) (CAS 29278-72-6)
- 1,1,3,3-Tetrabutyldistannoxane-1,3-diyl didodecanoate (CAS 3669-02-1)
- (E)-6,6'-(Ethene-1,2-diyl)bis(3-((4-morpholino-6-(phenylamino)-1,3,5-triazin-2-yl)amino)benzenesulfonic acid) (CAS 32466-46-9)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- Gadopiclenol Impurity 5 (CAS CATO-C4X-30025)
- Cefcapene Impurity 67 (CAS CATO-C4X-182467)
- 5-Chloro-2-methylindoline (CAS 68579-13-5)
- 3-[(4-Chlorophenyl)thio]propanoic Acid (CAS 6310-27-6)
- 4,7-Methano-1H-indene-2-carboxaldehyde, octahydro-5-methoxy- (CAS 86803-90-9)
- 7-Chloro-3-iodo-4H-chromen-4-one (CAS 343332-59-2)
- Rosuvastatin Impurity 135 (CAS CATO-C4X-1169135)
- Tert-butyl (2-amino-2-cyclopropylpropyl)carbamate (CAS 1269152-51-3)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com