Crizotinib Impurity 53 CAS CATO-C4X-102553
| CAS No. | CATO-C4X-102553 |
| Molecular Formula | C29H34ClFN8O |
| Molecular Weight | 565.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Crizotinib Impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Crizotinib Impurity 53 (CAS CATO-C4X-102553), a pharmacopoeial impurity reference standard (molecular formula C29H34ClFN8O, MW 565.08 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C29H34ClFN8O, Crizotinib Impurity 53 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 565.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C29H34ClFN8O |
| Molecular Weight | 565.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 8 |
Related Crizotinib Standards
- Crizotinib Impurity 50 (CAS CATO-C4X-102550)
- Crizotinib Impurity 21 (CAS 1428476-86-1)
- Crizotinib Impurity 01 (CAS 877399-51-4)
- Crizotinib impurity 26 (CAS CATO-C4X-102526)
- Crizotinib Impurity 72 (CAS CATO-C4X-102572)
- Crizotinib Impurity 60 (CAS CATO-C4X-102560)
- Crizotinib Impurity 44 (CAS CATO-C4X-102544)
- Crizotinib Impurity 57 (CAS CATO-C4X-102557)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com