Trelagliptin Impurity 27 CAS CATO-C4X-104627
| CAS No. | CATO-C4X-104627 |
| Molecular Formula | C12H7ClFN3O2 |
| Molecular Weight | 279.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Trelagliptin Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Trelagliptin Impurity 27 (CAS CATO-C4X-104627) is a certified pharmaceutical impurity reference standard with the molecular formula C12H7ClFN3O2 and a molecular weight of 279.65 g/mol.
The molecular framework of Trelagliptin Impurity 27 (C12H7ClFN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H7ClFN3O2 |
| Molecular Weight | 279.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Trelagliptin Standards
- Trelagliptin Impurity 18 (CAS CATO-C4X-104618)
- Trelagliptin Impurity 11 (CAS 1938080-42-2)
- Trelagliptin Impurity 28 (CAS CATO-C4X-104628)
- Trelagliptin Impurity 25 (CAS CATO-C4X-104625)
- Trelagliptin Impurity 56 (CAS CATO-C4X-104656)
- Trelagliptin Impurity 57 (CAS CATO-C4X-104657)
- Trelagliptin Impurity 69 (CAS CATO-C4X-104669)
- Trelagliptin Impurity 41 (CAS 1938080-43-3)
Recommended Standards
- Sodium 4-(4-chloro-2-hydroxybenzamido)butanoate (CAS 387825-07-2)
- 2-((3-Chloro-4-fluorophenyl)amino)-1H-purin-6(9H)-one (CAS 123994-77-4)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methylacrylohydrazide (CAS 338965-00-7)
- 6-Acetamido-4-nitropyridine-2-sulfonyl chloride (CAS 1393559-14-2)
- Pemetrexed Impurity 76 Disodium Salt (CAS CATO-C4X-172676)
- Loxoprofen Impurity 154 (CAS 90319-74-7)
- Docetaxel Impurity 62 (CAS CATO-C4X-161962)
- 3-(1,3-thiazol-2-yl)piperidine dihydrochloride (CAS 1258641-49-4)
- 4-(Difluoromethoxy)-3-iodobenzoic acid (CAS 1131588-14-1)
- 4-[(3-Fluorophenyl)carbonyl]benzonitrile (CAS 1365271-67-5)
- 2-Bromo-4-fluorobenzyl Alcohol (CAS 229027-89-8)
- 2,5-Diaminopyridin-3-ol (CAS 953018-37-6)
- N-Boc-1-amino-2-methyl-2-propanol (CAS 183059-24-7)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com