Ceritinib Impurity 21 CAS CATO-C4X-104821
| CAS No. | CATO-C4X-104821 |
| Molecular Formula | C10H7Cl2N3S |
| Molecular Weight | 272.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ceritinib Impurity 21.
Ceritinib Impurity 21 (CAS CATO-C4X-104821) is a certified pharmaceutical impurity reference standard with the molecular formula C10H7Cl2N3S and a molecular weight of 272.15 g/mol.
The molecular framework of Ceritinib Impurity 21 (C10H7Cl2N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ceritinib Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N3S |
| Molecular Weight | 272.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 37 (CAS CATO-C4X-104837)
- Ceritinib Impurity 41 (CAS CATO-C4X-104841)
- Ceritinib Impurity 44 (CAS CATO-C4X-104844)
- Ceritinib Impurity 46 (CAS CATO-C4X-104846)
- Ceritinib Impurity 51 (CAS CATO-C4X-104851)
- Ceritinib Impurity 81 (CAS CATO-C4X-104881)
- Ceritinib Impurity 17 (CAS CATO-C4X-1048917)
- Ceritinib Impurity 84 (CAS CATO-C4X-104884)
Recommended Standards
- Cyclopropyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (CAS 915402-05-0)
- N-(5-Bromo-2-fluorobenzyl)cyclopentanamine (CAS 1019532-16-1)
- 7-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one (CAS 915402-07-2)
- N-(2-bromo-4-fluorobenzyl)cyclopentanamine (CAS 1020977-94-9)
- Mianserin Impurity 106 (CAS CATO-C4X-1369106)
- Febuxostat Impurity 70 (CAS 1657014-33-9)
- Sildenafil Impurity 31 (CAS CATO-C4X-112831)
- 2,2,2-Trifluoroethyl (5-chloropyridin-2-yl)carbamate (CAS 1087788-67-7)
- 2-(2,6-difluorophenyl)cyclopropane-1-carboxylic acid (CAS 1157561-48-2)
- 2-(2-Bromo-6-(bromomethyl)-4-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1805253-78-4)
- Potassium 4-fluorobenzenesulfonate (CAS 52445-99-5)
- Rivaroxaban Impurity 15 (CAS CATO-C4X-109015)
- 3-Phenyl-4-[(phenylamino)methylidene]-4,5-dihydro-1H-pyrazol-5-one (CAS 338975-59-0)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com