Ceritinib Impurity 52 CAS CATO-C4X-104852
| CAS No. | CATO-C4X-104852 |
| Molecular Formula | C22H23N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ceritinib Impurity 52 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ceritinib Impurity 52 (CAS CATO-C4X-104852), a pharmacopoeial impurity reference standard (molecular formula C22H23N2O3Br, MW 443.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Ceritinib Impurity 52 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 443.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ceritinib Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23N2O3 Br |
| Molecular Weight | 443.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ceritinib Standards
- Ceritinib Impurity 86 (CAS /)
- Ceritinib (CAS 1032900-25-6)
- Ceritinib dihydrochloride (CAS 1380575-43-8)
- Ceritinib Impurity 88 (CAS 1823331-67-4)
- Ceritinib Impurity 87 (CAS 2976-70-7（free base))
- Ceritinib Impurity 85 (CAS 761440-17-9)
- Ceritinib Impurity 19 (CAS 771555-72-7)
- Ceritinib Impurity 2 (CAS 861343-73-9)
Recommended Standards
- Asenapine Impurity 6 (CAS 1847487-56-2)
- Iopamidol Impurity 42 (CAS CATO-C4X-145042)
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- 4-(α,β)-Hydroxy Rimantadine (CAS 117821-36-0)
- Thioctic Acid Impurity 12 (CAS 916746-61-7)
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- 8-chloro-5-methoxy-quinoline-6-carboxylic acid (CAS 926270-95-3)
- 2-(4-Methylthiazol-5-yl)ethyl decanoate (CAS 101426-31-7)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com