Ceritinib CAS 1032900-25-6
| CAS No. | 1032900-25-6 |
| Molecular Formula | C28H36ClN5O3S |
| Molecular Weight | 558.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ceritinib (C28H36ClN5O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ceritinib (CAS 1032900-25-6), molecular formula C28H36ClN5O3S and molecular weight 558.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ceritinib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H36ClN5O3S |
| Molecular Weight | 558.14 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 64 (CAS CATO-C4X-104864)
- Ceritinib Impurity 68 (CAS CATO-C4X-104868)
- Ceritinib Impurity 69 (CAS CATO-C4X-104869)
- Ceritinib Impurity 10 (CAS CATO-C4X-104810)
- Ceritinib Impurity 18 (CAS CATO-C4X-104818)
- Ceritinib Impurity 74 (CAS CATO-C4X-104874)
- Ceritinib Impurity 8 (CAS CATO-C4X-10488)
- Ceritinib Impurity 27 (CAS CATO-C4X-104827)
Recommended Standards
- 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoroheptyl (2,2,3,3,4,4,4-heptafluorobutyl) carbonate (CAS 1980086-56-3)
- EThyl perfluoro-9-methyl-8-oxadecanoate (CAS 1211025-06-7)
- 2H-Perfluoro-2-dodecenoic acid (CAS 70887-94-4)
- Chlorinated paraffins (Cl: 38 % from NMR), technical mix (CAS 61788-76-9)
- 2-(5-Bromo-2-chlorophenyl)acetic acid (CAS 177985-34-1)
- 2-(3-Formyl-1H-indol-1-yl)propanoic acid (CAS 166747-91-7)
- Naphthalen-1-yl(thiophen-3-yl)methanol (CAS 944697-82-9)
- 5,6-Diamino-1-butylpyrimidine-2,4(1H,3H)-dione (CAS 76194-08-6)
- 2-(Azocan-1-yl)pyrimidine-5-carbonitrile (CAS 1707586-61-5)
- 1775431-22-5 2-(3-chloro-4-methoxyphenyl)-1-{4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidin-1-yl}ethan-1-one BS-8217 (CAS 1775431-22-5)
- 2-Fluoro-3,4-dimethylpyridine (CAS 1227570-87-7)
- 5-(Pyridin-3-yl)isoxazol-3(2H)-one (CAS 72309-75-2)
- 9,12-Octadecadienoic acid (9Z,12Z)-, homopolymer, isodecyl ester (CAS 64059-72-9)
- Endo-[Glu]31-Liraglutide (CAS CATO-C4X-199234)
Why CATO?
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