Valsartan Impurity 40 CAS CATO-C4X-105740
| CAS No. | CATO-C4X-105740 |
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Valsartan Impurity 40 (C24H28N2O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Valsartan Impurity 40 (CAS CATO-C4X-105740, C24H28N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Valsartan Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H28N2O3 HCl |
| Molecular Weight | 428.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Valsartan Standards
- Valsartan Impurity 121 (CAS 1000986-63-9)
- (S)-(-)-Valsartan-d8 (valine-d8) (CAS 1089736-72-0)
- Valsartan-d9 (Major) (CAS 1089736-73-1)
- Valsartan Impurity 13 ( Valproic Acid EP Impurity A ) (CAS 109-52-4)
- Valsartan Impurity 35 HCl (CAS 1111177-20-8)
- Valsartan Impurity 9 (CAS 1111177-30-0)
- Valsartan Impurity 10 (CAS 114772-54-2)
- Valsartan Impurity 82 (CAS 1189547-11-2)
Recommended Standards
- Tirofiban Impurity 93 HCl (CAS CATO-C4X-125493)
- Trazodone impurity 56 (CAS CATO-C4X-177256)
- Oxiracetam Impurity 4 (CAS 62833-66-3)
- o-(Cyclobutylmethyl)hydroxylamine (CAS 773799-69-2)
- tert-Butyl 4-(hydroxymethyl)-4-methoxypiperidine-1-carboxylate (CAS 239073-94-0)
- (r)-2-([1,1'-biphenyl]-2-yl)-2-aminoethan-1-ol (CAS 1213065-20-3)
- Vonoprazan Impurity N27 (CAS 24367-50-8)
- (4,5-Dihydro-thiazol-2-yl)-isobutyl-amine (CAS 79146-95-5)
- 2-(2-(2-Bromoethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850567-53-2)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com