N-Nitroso Cinacalcet Impurity 4 CAS CATO-C4X-105974
| CAS No. | CATO-C4X-105974 |
| Molecular Formula | C26H24N4O3 |
| Molecular Weight | 440.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, N-Nitroso Cinacalcet Impurity 4 (CAS CATO-C4X-105974, C26H24N4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, N-Nitroso Cinacalcet Impurity 4 (C26H24N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 440.49 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), N-Nitroso Cinacalcet Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H24N4O3 |
| Molecular Weight | 440.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related N Standards
- N-Nitroso Sacubitril impurity 10 (CAS CATO-C4X-280910)
- N-Nitroso Lisinopril-D5 (CAS CATO-C4X-168131)
- N-Nitroso-Tamsulosin d4 Impurity (Mixture of isomers) (CAS CATO-C4X-118776)
- N-Nitroso Lemborexant (CAS CATO-C4X-304258)
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- N-Nitroso Tucatinib Impurity 27 (CAS CATO-C4X-260527)
Recommended Standards
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