N-Nitroso Cloxacillin Impurity 34 CAS CATO-C4X-159734
| CAS No. | CATO-C4X-159734 |
| Molecular Formula | C18H19ClN4O5S |
| Molecular Weight | 438.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
N-Nitroso Cloxacillin Impurity 34 (CAS CATO-C4X-159734) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19ClN4O5S and a molecular weight of 438.89 g/mol.
The molecular framework of N-Nitroso Cloxacillin Impurity 34 (C18H19ClN4O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), N-Nitroso Cloxacillin Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19ClN4O5S |
| Molecular Weight | 438.89 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
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- 4-Fluoro-4-(trifluoromethyl)piperidine hydrochloride (CAS 2241140-83-8)
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- 3-Amino-1-(3-methoxyphenyl)piperidin-2-one (CAS 1315365-05-9)
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