N-Nitroso Cinacalcet Impurity 5 CAS CATO-C4X-105976

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-105976
Molecular FormulaC22H21F3N2O
Molecular Weight386.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

N-Nitroso Cinacalcet Impurity 5 CAS CATO-C4X-105976 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 386.41 g/mol gives N-Nitroso Cinacalcet Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-Nitroso Cinacalcet Impurity 5 (CAS CATO-C4X-105976) is a certified pharmaceutical impurity reference standard with the molecular formula C22H21F3N2O and a molecular weight of 386.41 g/mol.

The molecular framework of N-Nitroso Cinacalcet Impurity 5 (C22H21F3N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures N-Nitroso Cinacalcet Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H21F3N2O
Molecular Weight386.41 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms2

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