Olanzapine Impurity 46 CAS CATO-C4X-117846
| CAS No. | CATO-C4X-117846 |
| Molecular Formula | C17H16ClN5O |
| Molecular Weight | 341.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Olanzapine Impurity 46 (CAS CATO-C4X-117846), a pharmacopoeial impurity reference standard (molecular formula C17H16ClN5O, MW 341.79 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Olanzapine Impurity 46 (C17H16ClN5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16ClN5O |
| Molecular Weight | 341.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Olanzapine Standards
- Olanzapine Impurity 59 (CAS CATO-C4X-117859)
- Olanzapine Impurity 60 (CAS CATO-C4X-117860)
- Olanzapine Impurity 61 (CAS CATO-C4X-117861)
- Olanzapine Impurity 01 (CAS 935272-10-9)
- Olanzapine Impurity 37 (CAS CATO-C4X-117837)
- Olanzapine Impurity 69 (CAS 2485860-97-5)
- Olanzapine Impurity 8 (CAS 1320360-87-9)
- Olanzapine Impurity 38 (CAS CATO-C4X-117838)
Recommended Standards
- 869937-73-5 tert-Butyl 4-(5-chloro-2-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate MFCD11553047 (CAS 869937-73-5)
- Lornoxicam Impurity 2 (CAS 70374-38-8)
- N-Benzyl-3-((3-chloro-4-methoxyphenyl)amino)-2-cyanoacrylamide (CAS 881560-27-6)
- Lornoxicam Impurity 98 (CAS CATO-C4X-201698)
- Ceritinib Impurity 82 (CAS CATO-C4X-104882)
- Alanyl Glutamine Impurity 51 (CAS CATO-C4X-197451)
- Teriflunomide Impurity 5 (CAS 220512-86-7)
- 2-{[6-chloro-2-(methylsulfanyl)pyrimidin-4-yl](2-hydroxyethyl)amino}ethan-1-ol (CAS 339017-88-8)
- Acetamiprid metabolite IM-1-4 (CAS 120739-62-0)
- Crisaborole Impurity 71 (CAS CATO-C4X-202171)
- N-(2-Methoxy-6-methylphenyl)acetamide (CAS 50868-76-3)
- tert-Butyl 4-((5,6-dimethoxy-2-(methoxycarbonyl)-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidine-1-carboxylate (CAS 652130-41-1)
- 4-Amino-N-cyclopropyl-3-methoxybenzamide (CAS 946826-55-7)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com