Cinacalcet impurity 82 CAS CATO-C4X-105982
| CAS No. | CATO-C4X-105982 |
| Molecular Formula | C22H26F3N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cinacalcet impurity 82 (C22H26F3NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Cinacalcet impurity 82 (CAS CATO-C4X-105982), a pharmacopoeial impurity reference standard (molecular formula C22H26F3NHCl, MW 397.91 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cinacalcet impurity 82 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H26F3N HCl |
| Molecular Weight | 397.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Cinacalcet Standards
- Cinacalcet Impurity 37 (CAS 100485-59-4)
- Cinacalcet Impurity N52 (CAS 1005450-55-4)
- Cinacalcet Impurity 29 (CAS 1020414-30-5)
- Cinacalcet Dihydro Impurity 1 Hydrochloride Salt (CAS 1020414-33-8)
- Cinacalcet Impurity 34 (CAS 1025064-33-8)
- Cinacalcet Impurity N97 (CAS 103324-39-6)
- Cinacalcet Impurity 50 (CAS 1034094-54-6)
- Cinacalcet Impurity 48 (CAS 10420-89-0)
Recommended Standards
- Cefazolin Impurity 30 (CAS CATO-C4X-157730)
- Iodixanol impurity 20 (CAS 111453-49-7)
- Atrasentan Impurity 58 (CAS 1063836-17-8)
- {[(4-tert-Butylphenyl)methyl]sulfanyl}methanimidamide hydrobromide (CAS 125988-33-2)
- 5-(1-Phenylpropyl)-1,3,4-oxadiazol-2-amine (CAS 7659-11-2)
- 4-(Methylthio)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-amine (CAS 175204-64-5)
- 5-(4-Chloro-1H-pyrazol-1-yl)-3-methoxythiophene-2-carboxylic acid (CAS 1707609-69-5)
- 1-(3-(Trifluoromethyl)phenyl)piperidine-4-carboxylic acid (CAS 847407-02-7)
- Deferasirox Impurity 2 (CAS CATO-C4X-14382)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
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