Edoxaban Impurity 80 CAS CATO-C4X-106380
| CAS No. | CATO-C4X-106380 |
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | 548.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Edoxaban Impurity 80 (CAS CATO-C4X-106380, C24H30ClN7O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Edoxaban Impurity 80 (C24H30ClN7O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 548.06 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | 548.06 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
Recommended Standards
- Edoxaban Impurity 53 (CAS 1255529-28-2)
- Edoxaban Impurity 81 (CAS CATO-C4X-106381)
- Edoxaban Impurity 82 (CAS CATO-C4X-106382)
- Bis((dibutoxyphosphorothioyl)thio)zinc (CAS 6990-43-8)
- Cefprozil Impurity 51 (CAS CATO-C4X-149251)
- Dexmedetomidine Impurity 38 (CAS CATO-C4X-123038)
- Capecitabine Impurity 47 (CAS CATO-C4X-102447)
- N-(2,2-Dimethoxyethyl)-5-iodopyrimidin-4-amine (CAS 1695374-63-0)
- Dibenzo[f,h]quinoxaline-2,3-dicarbonitrile (CAS 55408-49-6)
- 5-Oxo-N-(4-sulfamoylbenzyl)-1,4-thiazepane-3-carboxamide (CAS 1396631-95-0)
- tert-Butyl 4-((4-bromobenzyl)oxy)piperidine-1-carboxylate (CAS 930111-10-7)
- 2-Iodo-6-(trifluoromethyl)benzoic acid (CAS 914637-39-1)
- 2-Cyclohexyl-2-hydroxyacetonitrile (CAS 4354-47-6)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com