Edoxaban Impurity 5 CAS 2749802-54-6
| CAS No. | 2749802-54-6 |
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | 548.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Edoxaban Impurity 5.
Edoxaban Impurity 5 (CAS 2749802-54-6) is a certified pharmaceutical impurity reference standard with the molecular formula C24H30ClN7O4S and a molecular weight of 548.06 g/mol.
Edoxaban Impurity 5 (C24H30ClN7O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | 548.06 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
Recommended Standards
- Edoxaban Impurity 80 (CAS CATO-C4X-106380)
- Edoxaban Impurity 81 (CAS CATO-C4X-106381)
- Edoxaban Impurity 82 (CAS CATO-C4X-106382)
- Bis((dibutoxyphosphorothioyl)thio)zinc (CAS 6990-43-8)
- Lercanidipine Impurity 37 (CAS 75130-34-6)
- Ezetimibe Impurity 25 (CAS 404874-94-8)
- Cyclophosphamide Impurity 26 (CAS CATO-C4X-230626)
- N-PRopyl L-Z-isoleucinamide (CAS 1423037-51-7)
- 1-Amino-4-methylheptan-3-ol (CAS 126678-99-7)
- 5-(Hydroxymethyl)-4-methyloxazolidin-2-one (CAS 1781899-69-1)
- 8-Phenylxanthine (CAS 2879-14-3)
- 1-(6-Fluoropyridin-3-yl)cyclopropan-1-amine (CAS 1266129-28-5)
- Paricalcitol Impurity 23 (CAS CATO-C4X-138723)
- Hexapeptide-9 (CAS 885024-94-2)
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