Ibrutinib Impurity 112 CAS CATO-C4X-1064112
| CAS No. | CATO-C4X-1064112 |
| Molecular Formula | C32H24N8O2 |
| Molecular Weight | 552.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ibrutinib Impurity 112.
CATO supplies Ibrutinib Impurity 112 (CAS CATO-C4X-1064112), a pharmacopoeial impurity reference standard (molecular formula C32H24N8O2, MW 552.59 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C32H24N8O2, Ibrutinib Impurity 112 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 552.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H24N8O2 |
| Molecular Weight | 552.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Ibrutinib Standards
- Ibrutinib Impurity 115 (CAS CATO-C4X-1064115)
- Ibrutinib Impurity 148 (CAS CATO-C4X-1064148)
- Ibrutinib Impurity 118 (CAS CATO-C4X-1064118)
- Ibrutinib Impurity 142 (CAS CATO-C4X-1064142)
- Ibrutinib Impurity 22 (CAS CATO-C4X-106422)
- Ibrutinib Impurity 28 (CAS CATO-C4X-106428)
- Ibrutinib Impurity 163 (CAS CATO-C4X-1064163)
- Ibrutinib Impurity 168 (CAS CATO-C4X-1064168)
Recommended Standards
- Ddr1-in-1 (CAS 1449685-96-4)
- Cefpirome Impurity 49 (CAS CATO-C4X-120749)
- Cefpirome Impurity 15 (CAS CATO-C4X-120715)
- (4S,4'S)-2,2'-((Phenylphosphinediyl)bis(2,1-phenylene))bis(4-phenyl-4,5-dihydrooxazole) (CAS 2368937-53-3)
- Sildenafil Impurity 3 (CAS 139756-02-8)
- Fluorometholone Impurity 11 (CAS CATO-C4X-193311)
- Nicorandil impurity 58 (CAS CATO-C4X-190758)
- 1-Benzamidocyclopropanecarboxylic acid (CAS 72784-35-1)
- 3-Fluoro-5-(4-(trifluoromethoxy)phenyl)pyridin-4-amine (CAS 1261651-03-9)
- 1-Boc-4-[(2-bromo-6-fluorophenyl)(1-imidazolyl)methyl]piperidine (CAS 2033173-30-5)
- 4-(1H-Indol-4-yl)benzoic acid (CAS 406235-63-0)
- N-(1H-Indazol-5-yl)acetamide (CAS 95574-27-9)
- N-(2-Amino-6-cyclopropoxyphenyl)methanesulfonamide (CAS 1243466-33-2)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com