Ibrutinib Impurity 22 CAS CATO-C4X-106422
| CAS No. | CATO-C4X-106422 |
| Molecular Formula | C36H30O2P2 |
| Molecular Weight | 556.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ibrutinib Impurity 22 (CAS CATO-C4X-106422) is a certified pharmaceutical impurity reference standard with the molecular formula C36H30O2P2 and a molecular weight of 556.57 g/mol.
Structurally, Ibrutinib Impurity 22 (C36H30O2P2) contains organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 22.0, corresponding to approximately 22 ring(s) or double-bond equivalent(s). With a molecular weight of 556.57 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ibrutinib Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C36H30O2P2 |
| Molecular Weight | 556.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibrutinib Standards
- Ibrutinib Impurity 28 (CAS CATO-C4X-106428)
- Ibrutinib Impurity 118 (CAS CATO-C4X-1064118)
- Ibrutinib Impurity 112 (CAS CATO-C4X-1064112)
- Ibrutinib Impurity 115 (CAS CATO-C4X-1064115)
- Ibrutinib Impurity 148 (CAS CATO-C4X-1064148)
- Ibrutinib Impurity 142 (CAS CATO-C4X-1064142)
- Ibrutinib Impurity 63 (CAS CATO-C4X-106463)
- Ibrutinib Impurity 64 (CAS CATO-C4X-106464)
Recommended Standards
- Aloeresin D (CAS 105317-67-7)
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- Tigecycline Impurity 7 (CAS 1268494-40-1)
- N-(3-Fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (CAS 1394820-69-9)
- Triclopyr impurity D (CAS CATO-CCPD103607)
- Erlotinib impurity 142 (CAS CATO-C4X-1069142)
- Iobitridol Impurity 36 (CAS CATO-C4X-317836)
- N-[(1-phenyl-1H-pyrazol-4-yl)methylidene]hydroxylamine (CAS 99185-49-6)
- tert-Butyl N-[(2-chloro-4-fluorophenyl)methyl]carbamate (CAS 1881292-97-2)
- 1-(5-BROMO-2-HYDROXY-3-NITROPHENYL)ETHANONE 3'-BROMO-6'-HYDROXY-5'-NITROACETOPHENONE 3-BROMO-6-HYDROXY-5-NITROACETOPHENONE 5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE 5'-BROMO-3'-NITRO-2'-HYDROXYACETOPHENONE 70978-54-0 BC003709 (CAS 70978-54-0)
- 1-(4-Fluoro-2-methylphenyl)-3-methylbutan-1-one (CAS 1342783-04-3)
- (S)-3-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-((2,2-difluoroethyl)amino)-2-oxoethyl)-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxamide (CAS 1414642-93-5)
- (4-Amino-3-chloro-5-(difluoromethyl)pyridin-2-yl)methanol (CAS 1805328-98-6)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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