Ibrutinib Impurity 189 CAS CATO-C4X-1064189
| CAS No. | CATO-C4X-1064189 |
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ibrutinib Impurity 189 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ibrutinib Impurity 189 (CAS CATO-C4X-1064189), a pharmacopoeial impurity reference standard (molecular formula C30H31N5O4, MW 525.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ibrutinib Impurity 189 (C30H31N5O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 525.60 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ibrutinib Impurity 189 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H31N5O4 |
| Molecular Weight | 525.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Ibrutinib Standards
- Ibrutinib Impurity 65 (CAS CATO-C4X-106465)
- Ibrutinib Impurity 188 (CAS CATO-C4X-1064188)
- Ibrutinib Impurity 141 (CAS CATO-C4X-1064141)
- Ibrutinib Impurity 26 (CAS CATO-C4X-106426)
- Ibrutinib Impurity 27 (CAS CATO-C4X-106427)
- Ibrutinib Impurity 162 (CAS CATO-C4X-1064162)
- Ibrutinib Impurity 17 (CAS CATO-C4X-106417)
- Ibrutinib Impurity 50 (CAS CATO-C4X-106450)
Recommended Standards
- (S)-tert-butyl 3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methylbut-1-ynyl)-1H-imidazo[4,5-c]pyridin-7-yloxy)methyl)piperidine-1-carboxylate (CAS 937174-75-9)
- Imatinib (Piperidine)-N,N-DiOxide (CAS 571186-93-1)
- BDTO26-Br (CAS 1416004-37-9)
- Ceftazidime Impurity 105 (CAS CATO-C4X-1212105)
- Quetiapine Fumarate EP Impurity V (CAS 2204369-14-0)
- Nitroso Perindopril EP impurity P (CAS CATO-C4X-125253)
- Vonoprazan Impurity 254 DiHCl (CAS CATO-C4X-1020254)
- Methyl xyloside (CAS 612-05-5)
- 4-[(propan-2-ylamino)methyl]benzonitrile (CAS 91350-01-5)
- 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,11,11,12,12,13,13,14,14,15,15,16,16,17,17,17-Triacontafluoroheptadecane-8,10-dione (CAS 36554-97-9)
- 2-(6-Methoxynaphthalen-2-yl)propanenitrile (CAS 86603-94-3)
- 2-((4-Chlorophenoxy)methyl)-1,4-dioxane (CAS 327087-79-6)
- 2-((Cyclohexyloxy)methyl)benzaldehyde (CAS 1443305-16-5)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com