Empagliflozin impurity 244 CAS CATO-C4X-1065244
| CAS No. | CATO-C4X-1065244 |
| Molecular Formula | C21H25ClO2 |
| Molecular Weight | 344.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin impurity 244 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Empagliflozin impurity 244 (CAS CATO-C4X-1065244, C21H25ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Empagliflozin impurity 244 (C21H25ClO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 344.88 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H25ClO2 |
| Molecular Weight | 344.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 114 (CAS 1459754-32-5)
- Empagliflozin Impurity 43 (CAS CATO-C4X-106543)
- Empagliflozin Impurity 112 (CAS 1628918-34-2)
- Empagliflozin impurity 263 (CAS CATO-C4X-1065263)
- Empagliflozin impurity 264 (CAS CATO-C4X-1065264)
- Empagliflozin Impurity 292 (CAS CATO-C4X-1065292)
- Empagliflozin impurity 250 (CAS CATO-C4X-1065250)
- Empagliflozin impurity 207 (CAS CATO-C4X-1065207)
Recommended Standards
- 2-(2-(4-Chlorophenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-2-cyclohexylethan-1-ol (CAS 1335213-32-5)
- Loratadine Impurity 101 (CAS CATO-C4X-1426101)
- JNJ-40411813, 98% (HPLC) (CAS 1127498-03-6)
- Cetirizine Impurity 37 (CAS CATO-C4X-158237)
- Meropenem Impurity 59 (CAS CATO-C4X-130959)
- Tunodafil Impurity 13 (CAS CATO-C4X-311013)
- Lifitegrast Impurity 110 (CAS 2091680-73-6)
- Ethyl 4-thioxo-6-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate (CAS 1216580-67-4)
- 4'-Chloro-[1,1'-biphenyl]-2,5-dione (CAS 20307-43-1)
- 3-Chloro-N-(2-(2-methyl-1h-imidazol-1-yl)ethyl)aniline dihydrochloride (CAS 1423026-23-6)
- 1-Benzyl-3-bromo-1H-pyrazole-5-carbaldehyde (CAS 2095051-65-1)
- (3-Bromo-5-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1227563-37-2)
- 7-Amino-2-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 1203898-13-8)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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