Empagliflozin Impurity 112 CAS 1628918-34-2
| CAS No. | 1628918-34-2 |
| Molecular Formula | C13H9ClFI |
| Molecular Weight | 346.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Empagliflozin Impurity 112 (CAS 1628918-34-2, C13H9ClFI) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H9ClFI, Empagliflozin Impurity 112 contains fluorine/chlorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 346.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H9ClFI |
| Molecular Weight | 346.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 244 (CAS CATO-C4X-1065244)
- Empagliflozin Impurity 114 (CAS 1459754-32-5)
- Empagliflozin Impurity 43 (CAS CATO-C4X-106543)
- Empagliflozin impurity 263 (CAS CATO-C4X-1065263)
- Empagliflozin impurity 264 (CAS CATO-C4X-1065264)
- Empagliflozin Impurity 292 (CAS CATO-C4X-1065292)
- Empagliflozin impurity 250 (CAS CATO-C4X-1065250)
- Empagliflozin impurity 207 (CAS CATO-C4X-1065207)
Recommended Standards
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- Oleyl Mesylate (CAS 35709-09-2)
- 2-Bromo-9-(3-chloro-5-fluorophenyl)-6,7-dihydro-5H,9H-[1,2,4]triazolo[5,1-c][1,4]oxazepine (CAS 2412990-82-8)
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- tert-Butyl (2-(5-acetyl-4-hydroxypyridin-2-yl)ethyl)carbamate (CAS 1393551-78-4)
- 2-(4-Benzyl-5-sulfanyl-4h-1,2,4-triazol-3-yl)acetic acid (CAS 170746-99-3)
- Apremilast Impurity 55 (CAS 885268-06-4)
- (2R,3S,5R,6R,7R,8R)-2-Hydroxy-12-isopropenyl-7-methyl-11-oxospiro[4,10-dioxatetracyclo[7.2.1.02,7.03,5]dodecane-6,2\'-oxiran]-8-yl acetate 2749-28-2 (CAS 2749-28-2)
- Tert-butyl (1-(pyrazin-2-yl)azetidin-3-yl)carbamate (CAS 1389313-26-1)
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