Empagliflozin Impurity 294 CAS CATO-C4X-1065294
| CAS No. | CATO-C4X-1065294 |
| Molecular Formula | C20H23ClO5 |
| Molecular Weight | 378.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Empagliflozin Impurity 294 (CAS CATO-C4X-1065294) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23ClO5 and a molecular weight of 378.85 g/mol.
Empagliflozin Impurity 294 (C20H23ClO5) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Empagliflozin Impurity 294 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23ClO5 |
| Molecular Weight | 378.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 295 (CAS CATO-C4X-1065295)
- Empagliflozin Impurity 301 (CAS CATO-C4X-1065301)
- Empagliflozin impurity 327 (CAS CATO-C4X-1065327)
- Empagliflozin Impurity 51 (CAS CATO-C4X-106551)
- Empagliflozin Impurity 240 (CAS CATO-C4X-1065240)
- Empagliflozin Impurity 146 (CAS CATO-C4X-1065146)
- Empagliflozin impurity 194 (CAS CATO-C4X-1065194)
- Empagliflozin Impurity 104 (CAS 915095-84-0)
Recommended Standards
- N-[6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-2-chloro-N-(3-methylbutyl)acetamide (CAS 571917-23-2)
- N-(4-Chloro-5-formyl-3-phenyl-2(3H)-thiazolylidene)benzenesulfonamide (CAS 726153-76-0)
- N-(3-((4-Chlorophenyl)amino)-3-oxo-1-phenylpropyl)benzamide (CAS 868268-60-4)
- Darolutamide Impurity 44 (CAS CATO-C4X-310644)
- Indocyanine Green Impurity 60 (CAS CATO-C4X-250360)
- Resmetirom Impurity 39 (CAS CATO-C4X-291239)
- Estriol Impurity 14 (CAS 1497406-77-5)
- rel-(3R,4S)-1-(tert-Butoxycarbonyl)-4-(p-tolyl)pyrrolidine-3-carboxylic acid (CAS 1360437-60-0)
- Ethyl 2-(2-aminooxazol-5-yl)acetate (CAS 1120271-63-7)
- 1-(3-Fluoro-2-methylphenyl)-3-methylbutan-1-one (CAS 1443344-19-1)
- Podophyllotoxin impurity 7 (CAS CATO-C4X-24257)
- Nintedanib Nintedanib Impurity 88 (CAS CATO-C4X-181488)
- 2-((5-Methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio)-N'-(2-(p-tolyloxy)acetyl)acetohydrazide (CAS 335223-01-3)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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