Empagliflozin impurity 327 CAS CATO-C4X-1065327
| CAS No. | CATO-C4X-1065327 |
| Molecular Formula | C24H23ClO2 |
| Molecular Weight | 378.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Empagliflozin impurity 327.
Empagliflozin impurity 327 (CAS CATO-C4X-1065327) is a certified pharmaceutical impurity reference standard with the molecular formula C24H23ClO2 and a molecular weight of 378.89 g/mol.
Based on its molecular formula C24H23ClO2, Empagliflozin impurity 327 contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 378.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Empagliflozin impurity 327 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H23ClO2 |
| Molecular Weight | 378.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 294 (CAS CATO-C4X-1065294)
- Empagliflozin Impurity 295 (CAS CATO-C4X-1065295)
- Empagliflozin Impurity 301 (CAS CATO-C4X-1065301)
- Empagliflozin Impurity 51 (CAS CATO-C4X-106551)
- Empagliflozin Impurity 240 (CAS CATO-C4X-1065240)
- Empagliflozin impurity 194 (CAS CATO-C4X-1065194)
- Empagliflozin Impurity 146 (CAS CATO-C4X-1065146)
- Empagliflozin Impurity 104 (CAS 915095-84-0)
Recommended Standards
- Ospemifene E-Isomer (CAS 238089-02-6)
- N-(2-Chlorophenyl)-2-(2-(1-(pyridin-2-yl)ethylidene)hydrazinecarbonothioyl)hydrazinecarbothioamid (CAS 127142-14-7)
- 3-Butyl-5-chloro-3-methyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-20-5)
- 4-Bromo-2-(difluoromethyl)-6-iodo-3-nitropyridine (CAS 1804846-82-9)
- Ibuprofen Impurity 78 (CAS 51146-56-6)
- (S,S)-Formoterol Impurity (CAS 67346-48-9)
- N-Nitroso Felodipine EP Impurity C (CAS CATO-C4X-109421)
- (3-Bromo-6-chloro-2-fluorophenyl)(pyrrolidin-1-yl)methanone (CAS 2586126-52-3)
- Sorafenib EP Impurity E (CAS 284670-98-0)
- 6-Chloro-3-(2-cyclopropyl-6-methylphenoxy)pyridazin-4-ol (CAS 499223-49-3)
- 4-(4-bromo-3-methoxyphenyl)thiazol-2-amine (CAS 443290-56-0)
- 2-(4-Bromo-3-fluorophenyl)-5-butyl-1,3-dioxane (CAS 1363339-35-8)
- 5,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-one (CAS 22406-36-6)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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